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Pore-forming cytolysins from sea anemones were used in the construction of ITs targeted to different cell types including tumour cell lines and the parasite Giardia duodenalis.
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Chimeric calsequestrin and its targeting to the junctional sarcoplasmic reticulum of skeletal muscle.
Moreover, silibinin was the only STAT3i predicted to establish direct interactions with DNA in its targeting to the STAT3 DBD.
Together, our findings have uncovered the efferent circuit controlling biogenesis of beige fat and provide support for its targeting to treat obesity.
Previously, we have successfully developed an EGF-conjugated HPPS nanoparticle and tested its targeting to cancer cells in vitro and in vivo (Zhang et al. 2010).
SAS-6 phosphorylation by ZYG-1 in C. elegans triggers its targeting to the newborn centriole.
Kif2b binds to Cep170 through its C terminus to enhance its targeting to the spindle.
Since Cu is essential for PC, its targeting to the thylakoid lumen has to be finely tuned.
The phosphorylation of AQP2 at serine 256 is critical in its targeting to the apical cell surface by ADH stimulation.
The neuronal activity regulates palmitoylation of AKAP79/150, and mediates its targeting to postsynaptic membrane lipid rafts and dendritic endosomes.
Until it cut its target to 17,000 in August the company had forecast output of 25,000 to 30,000 tonnes.
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