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Inter started only one Italian, the striker Giampaolo Pazzini, in its lineup or its substitutions.
Negredo's goal came too late and came at a time when Munich was making its substitutions, withdrawing Robben and Ribéry and Schweinsteiger for another day.
However, there is still debate on the optimal percentage of carbohydrates and its substitutions in the calorie reduced diet for patients with type 2 diabetes [ 7].
Phylogenetic analysis of miR-2 family showed that the cis-miR-2 can be easily found for its substitutions and insertions in the middle of miRNA, just behind the "seed region"; In contrast, the cis-miR-87 was conserved in the middle, and mosquitoes (above red line) and some other insects including B. mori and D. melanogaster innovated at the position.
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There is the possibility that the ITS1 and ITS2 sequences might be subject to different selective pressures [ 42] resulting in region-specific rates of ITS substitution when natural selection is stronger than genetic drift.
In further support of this conclusion, the mean ITS substitution rate was also marginally positively correlated with transformed values of relative extinction, ε: Least squares regression of contrasts (through origin), r2 = 0.191, slope = 58.30, F1,11 = 2.60, P = 0.13.
It is an important catalytic residue and its substitution to glutamic acid (p.Gly466Glu) originates a protein with higher ERK signaling than wild-type BRAF but a diminished, although constitutively active, TK activity [ 41].
In its substitution of visual impact for creative ambition, it reminds me of a properly profitable comic-book film sequel.
In particular, the substituted furan moiety on indazole skeleton as well as its substitution pattern turns out crucial for the high HIF-1 inhibition.
It is hard to find some substance insulin-mimetic for its substitution [ 32].
To better understand the evolutionary dynamics of the BoxG18A mutation, we sought to determine when it appeared in the evolving population and the time course of its substitution.
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CEO of Professional Science Editing for Scientists @ prosciediting.com