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44 Idraparinux is another synthetic pentasaccharide that indirectly inhibits factor Xa. It differs from fondaparinux in its substantially longer half-life, with a 2.5 mg weekly sc dose in studies, and seemed promising in phase II studies.
Firstly, although AS & AQ monthly is the most costly IPTc regimen to deliver (at US$13.16 per child enrolled or US$14.79 per child fully adherent, it is the most cost effective option given its substantially higher protective efficacy.
(While we can detect Saa3 in vivo, we were unable to detect it in our explant system, likely due to its substantially lower levels of expression relative to Saa1 and 2).
At a $90 per barrel oil price, this technology could be unprofitable for a modest price of carbon dioxide (CO2) emissions because of its substantially higher carbon intensity.
"DfID's oversight of PIDG has overall been insufficient to ensure value for money from its substantially increased funding," the NAO report said.
The Z10 is the first of a series of smartphones based on a new operating system that BlackBerry hopes will revive its substantially diminished fortunes.
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But since it has been able to reduce its inventory costs substantially, its gross margin remained the same as last year, at 25percentt.
Sky secured the rest, but it had to raise its price substantially.
So it is – still – up to Kraft to improve its terms substantially come mid-January, when the real action begins.
Costly programming efforts have failed to increase its ratings substantially.
The carmaker will increase its dividend "substantially," he said.
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