Although this approach has identified a significant number of NB-specific genes, its specificity is limited and it cannot be used to characterize certain cell subpopulations or to compare wild-type with tumor mutant NBs.
The sensitivity of FAST scans in detecting intraperitoneal hemorrhage is 75-78% and its specificity is 98-100%, suggesting it is a useful tool to confirm the presence of hemoperitoneum and hemopericardium [31, 32].
Its specificity is not strict since it can also recognize alanine, β-alanine, aspartate, and propanoate as substrates.
However, as it ignores the binding partners and the interactions created across the interfaces it has a high false positive rate, its specificity is 0.44 and its area under the ROC curve is 0.58 (see table in Additional file 2).
PSA is a quite accurate diagnostic test, but its specificity is too low because PSA is a prostate-specific but not a prostate cancer-specific marker: for this reason, those biopsies requested for altered PSA levels are often negative.
It is a nitrilase (from conserved domain cl11424) but its specificity is unknown.
However, since it depends on cytological changes but not on bacterial detection, its specificity is confounded by inflammatory reactions other than those caused by tuberculosis [ 13].
It's funny (although, with her thick Scottish accent, frequently impenetrable), but its specificity is jarringly at odds with the rest of the production.
However, its specificity is less than ideal.
Its sensitivity for diagnosis of pneumothorax is 66% and its specificity is 100%[43]].
However, its specificity is limited due to increased FDG uptake in benign lymphadenitis, other inflammatory processes or after treatment.
