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Interestingly, FAK inhibition augmented docetaxel-mediated apoptosis in ovarian cancer cells [49], [50], suggesting that the effects of the cytoskeleton and its regulators are not limited to regulation of cell morphology, adhesion and motility.
It is unclear if complement and its regulators are beneficial or detrimental for the progression of cancer.
Multiple agents targeting hepcidin and its regulators are under development as novel therapeutics for iron disorders.
Chromatin and its regulators are important controllers of reprogramming, and reprogramming factor levels, stoichiometry, and extracellular conditions influence the outcome.
One country that has not yet blessed the proposed transaction is China, though its regulators are expected to approve the deal.
Consistent with the diverse roles of the cohesin complex in chromosome biology, mutations in genes encoding cohesin and its regulators are found in different types of cancer and in developmental disorders such as Cornelia de Lange Syndrome.
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It increasingly looks as if BP and its regulators were too confident that the supposedly failsafe blowout preventer would seal the well in the event of catastrophe.
Shiller contends that it is possible that the government and its regulators were excessively focused on preventing recession and deflation because they honestly saw the home price increases as continuing -- if at a reduced rate -- indefinitely, even if they were to implement a monetary policy that would feed the bubble (p. 48).
Its regulators were also keen.
At the heart of the dispute between Fannie Mae and its regulators is a complex accounting rule, known as SFAS 133.
They depicted a company so troubled that its crisis meetings were called "Def-Con calls" and so callous to risks that its regulators were confounded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com