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Over the last years, increasing attention has been paid to skin engineering due to its predominant function in body integrity.
Although 必 bì seems to be the only direct marker of strict deontic modality in LAC and Han Chinese, the function as an epistemic modal adverb expressing (mostly) future certainty is evidently its predominant function from the earliest instances on.
While its predominant function is as a SOD mimetic scavenging superoxide anion, other reports indicated its potential to scavenge peroxinitrate as well [38].
However, probably as a consequence of its predominant function in stimulating cell proliferation, deregulation of the TrkA pathway is common in cancers [ 5].
LRP2, also known as megalin, is a member of the lipoprotein receptor-related protein (LRP) family, with its predominant function in lipid metabolism through controlling the activity of lipoprotein lipase [ 7, 8].
Its contributions to transcriptional regulation are mediated in several different ways: although PARP-1 can act as a promoter-specific co-regulator and by binding to specific enhancer sequences and insulators, its predominant function in transcription can probably be attributed to a modulatory influence on chromatin structure.
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Transcription factor E2F1 gains more attention due to its predominant functions in controlling cell cycle, tumorigenesis, apoptosis, and aggressiveness [ 21, 26- 29].
In addition to its predominant role in motor functions, it has been shown that the cerebellum is involved in higher cognitive and emotional processes [ 56].
Although LiCl may have off-targets effects, its predominant known function in colorectal epithelium is a Wnt mimetic and suppressor of GSK3 β (Dihlmann et al, 2003).
Lineage-specific transitions of this kind could alter the conformational ensemble accessible to the same protein in different species, causing a functional change, even if the predominant function remains conserved.
It is known that disease resistance is the predominant function for plant NB-LRR-encoding genes [ 1], but their other biological roles should not be precluded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com