Sentence examples for its overall efficacy from inspiring English sources

Human-rights groups applauded its founding, but, in an assessment a year later, the Center for American Progress, a Democratic think tank, concluded that "the continuing tragedy in Syria has cast a pall over the board's work and has led many to sharply question its overall efficacy".

Several previous studies have assessed the ability of FDG PET-CT to detect primary biliary tumours; however, few report its overall efficacy in the management pathway of patients with primary biliary malignancy.

Initially, the GRP-R agonist AMBA [5] showed promising results for successful clinical use; however, its agonistic activity has caused acute gastrointestinal side effects such as nausea, abdominal pain, and emesis and its overall efficacy has been rather unsatisfactory in a phase I trial [6].

Then the business can improve its overall efficacy.

19 In conclusion, bortezomib monotherapy demonstrated definitive signs of activity in patients with heavily-treated relapsed and refractory ATL; however, its overall efficacy was not sufficiently promising.

We believe that mean 10%% ADC value had intrinsic advantages, although its overall efficacy was inferior to pCASL and DSC-PWI in this study.

The likely adverse effect of calcium supplements on cardiovascular events, taken together with the possible adverse effect on incidence of hip fracture 2 58 and its modest overall efficacy in reducing fracture (about 10% reduction in total fractures) 2 3 suggest that a reassessment of the role of calcium supplements in the prevention and treatment of osteoporosis is warranted.

Despite of tremendous therapeutic potential of curcumin against cancer including neuroblastoma, low bioavailability, short half life, and photodegradation are the major limiting factors of curcumin its overall therapeutic efficacy (Aggarwal et al. 2003a, b; Anand et al. 2007; Ansari et al. 2005).

Besides the inhibition of coagulation, heparins exhibit many other biological activities which are involved in its overall therapeutic efficacy.

Taken together, these results suggest that while the conjugation of ATAP to the MCNPs increases its overall chemotherapeutic efficacy, release of ATAP from the MCNPs is essential to achieve the maximal apoptotic effect.

Since the relief of joint pain afforded by paracetamol is comparable with that achievable with NSAIDs, paracetamol merits a trial as initial therapy, based on its overall cost, efficacy, and toxicity profile [ 3, 7].