It is noteworthy that, besides its major role as the Na+/K+ pumps, Na+/K+-ATPase is involved in tumor proliferation and migration through activating its downstream Src-ERK signaling components (Prassas and Diamandis, 2008).
In addition to its major role in bone resorption, it has been demonstrated that cathepsin K plays a critical role in cartilage degradation as well.
Using different mechanisms (through both cell-bound and soluble proteins) it is able to discriminate self from non-self and its major role is in the induction and progression of inflammation against microbial pathogens.
The cbb 3 respiratory complex has high affinity for oxygen, and besides its major role in respiration under conditions of low oxygen pressure, it has been implicated in signal transduction in Rhodobacter sphaeroides [ 41].
Its major role would be to put a peace settlement into operation, especially with regard to protecting minorities.
Hydrogen bonding is important in biology because of its major role in determining the configurations of molecules.
François Hollande, the Socialist presidential frontrunner, praised the vitality of French cinema and its major role in France's cultural influence abroad.
Its major role is to moderate body temperature and blood pressure by forming a peripheral shunt, an alternate route for the blood.
Financial help has come from foundations and from Corning Incorporated, which despite its major role in the community quietly contributed $200,000 but has not asked employees to take part in the training.
They cite its major role in November's election, asserting that without labor's support for Mr. Gore, Mr. Bush would have won easily and that Mr. Gore would have lost crucial swing states, including Wisconsin, Pennsylvania and Michigan.
It is therefore surprising that during the present elections, at a time of increasing economic insecurity, Poles appear to have decided to support the ruling party by confirming its major role in the European parliament.
