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A commercial plant extract derived from olive tree leaf (Olea europaea) (LExt) and its major compound, oleuropein (Ole), inhibited the in vitro infectivity of the viral haemorrhagic septicaemia virus (VHSV), a salmonid rhabdovirus.
Hepatoprotective activity of investigated essential oil isolated from rosemary can be attributed to 1,8-cineole, as its major compound.
In this study, we attempted to evaluate the effects of ID and its major compound caffeic acid on allergic inflammation in vivo and in vitro.
In the present work, we have focused on the phytochemical study, cytotoxicity and antifungal activity of the fresh xylem sap of H. courbaril and its major compound fisetin (1).
In a study, Artemisia lavandulaefolia EO and its major compound 1,8-cineole have been shown to adopt the above route for mitochondrial and MAPKs pathways resulting in apoptosis in the mouth cancer, KB cells [ 23].
On the other hand, Lee et al. [ 53] proved that a flavonol-rich hexane fraction from Rhus verniciflua stokes and its major compound fisetin affected differently the TNF- α and IL-6 production in vitro.
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In this way, an essential oil is defined not only by its major compounds, but rather by a majority of all its compounds (Zouari [2013]).
In addition, its major compounds decreased p65 NF-κB phosphorylation.
The main bioactive compound responsible for the antidepressant effects of St. John's wort extracts is its major lipophilic compound, hyperforin (Figure 1, compound 1).
In a randomized crossover study in healthy men, we investigated the effects of orange juice and its major polyphenolic compound hesperidin on a panel of immune cell functions, including cytokine secretion by leukocytes, lytic activity of NK cells, and the Reactive Oxygen Species (ROS) burst by polymorphonuclear neutrophil cells (PMN).
We assessed the ability of its ethanolic and phenolic-rich extracts and its major phenolic compound, sinapinic acid, possessing histone deacetylase (HDAC) inhibitory activity to inhibit proliferation of 5 human cancer cell lines.
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