Sentence examples for its major activity from inspiring English sources

Its major activity was against melanoma cancer cell lines.

Although non-genomic actions of the AR have been proposed [37], its major activity is thought to be a consequence of DNA engagement and transcriptional regulation.

Considering the neuronal plasticity we have described before, Drosophila with its major activity peaks during the daylight-transition phases at dawn and dusk provides a valuable model system to study the circadian neuronal mechanisms of visual system- and visual behavior adaptation.

PNS and its major activity components Rg1, Rb1 and R1 suppressed tumor growth and simultaneously attenuated myocardial ischemia.

Importantly, CLSP may be the first bioactive peptide that is mainly secreted by the skin and exerts its major activity in the CNS.

Although Tgl1 also contributes to TAG hydrolysis, its major activity is as a steryl ester hydrolase, in conjunction with the YEH1 - and YEH2 -encoded enzymes (Jandrositz et al. 2005; Koffel et al. 2005).

In this paper, we introduce the EasyWinWin process and describe its major activities.

Tramadol-related analgesic effects are mediated by its antagonist activity on the norepinephrine and serotonin transporters in addition to the agonist activity of its major active metabolite M1 on the mu-opioid receptors.

However, because APE1 is a multifunctional protein with redox activity and acetylation modification in addition to its major repair activity, the particular APE1 function that may play a more important role in melphalan resistance is unknown.

Second, Eskom identified the sources of impact with respect to its three major activities: building new facilities, operating these facilities and, ultimately, providing electricity to South Africans.

Multiple mechanisms of action of doxorubicin have been elucidated, but its major antitumor activity is thought to occur through the generation of DNA breaks in the tumor cell.