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Hydrogen peroxide is involved in many types of cell injury and exerts most of its injurious effects in conjunction with chelatable iron.
Furthermore, AMPK inhibits iNOS (inducible NOS) activity, which is known for its injurious effects through the generation of NO [ 42].
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The overall finding was that at about 20 miles an hour, "the air bag's protective effect becomes large enough to offset its injurious effect" -- with the net effect of providing more benefit than harm.
However, its injurious effect may also impact the underlying myocardium.
In the present study, we investigated the biological safety of platinum nanoparticles in mice and found that platinum particles of less than 1 nm induced kidney injury, although the injurious effects were reduced by increasing the nanoparticle size.
It is even possible that injurious effects of antibody on articular cartilage may precede and even initiate subsequent inflammatory events that contribute to ultimate joint destruction, and provides a further rationale for the successful use of combination therapies [ 47].
In the liver, preconditioning prevented postischemic ROS generation and hepatic injury as well as the injurious effects in the lung following liver transplantation.
The injurious effects of an electrical current passing through the body are determined by its voltage, its amperage, and the resistance of the tissues in the pathway of the current.
In addition, TNFα may have direct injurious effects on the podocyte, the target of injury in nephrotic disorders.
Recently, food supplementation with antioxidants has been the major focus of attention amongst the health professionals across the world to explore it as a strategy to protect against the injurious effects of oxidative stress.
It is thus possible that ACE-Is cause their injurious effects in CIN by indirectly inhibiting formation of TGF- β1.
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CEO of Professional Science Editing for Scientists @ prosciediting.com