Sentence examples for its inducers from inspiring English sources

In addition, methylation accumulation is known to be caused by exposure to its inducers, such as chronic inflammation, 35 and cancer risk prediction using accumulated methylation is considered to take account of the life history of individuals.

The combination of IL-6 and its inducers TNF-α and IL-1β [ 35] promotes tumor growth and survival in cancer patients through maintenance of chronic inflammation and induction of a tumor-supporting microenvironment [ 19, 36].

14 19 24 Since methylation induced in stem cells can only persist for a long time without its inducer, the methylation level in gastric mucosa without H. pylori infection could be considered to reflect epigenomic damage accumulated in stem cells.

In this study, we demonstrate that the acetamidase promoter from Mycobacterium smegmatis responds in a dose-dependent manner to different concentrations of its inducer acetamide.

This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen receptor ligand, tamoxifen.

Consider a transcription factor whose concentration is X, that binds its inducer s with a dissociation constant K s.

NANOG is also repressed by FGF4, which in this case would be low, since its inducer OCT4-SOX2 is OFF.

In turn, the enzyme activates its inducer to a more cytotoxic product, which results in a remarkable IC50 of 10 nM under these conditions [ 22].

The purpose of the current study was to determine whether the transcription factor HSF-1 and its inducer GGA can affect expression of SAP97.

It is also possible that gastric-produced neurotensin may, at least in part, counteract pro-fibrotic action of its inducer, the leptin in the hepatic parenchyma.

We examined whether the heat shock transcription factor 1 (HSF-1) and its inducer geranylgeranylacetone (GGA) could affect the expression of Kv1.5 channels and its anchoring protein, synapse associated protein 97 (SAP97).