In its highest stage of development, it was constructed by excavating parallel trenches about 40 feet apart to provide longitudinal drainage a hallmark of Roman road engineering.
At its highest stage Lake Bonneville covered an area of about 52,000 square kilometres, and its maximum depth was approximately 370 metres.
The life of man, he came to feel is a constant struggle between the individualist and the collective but at its highest stage "the individual is submerged in the family … the family in the nation … and so the Nation … in the highest attainment of human collectivity the world has yet seen … the empire".
Word of the case spread on a day when the city was at its highest stage of alert anyway, as President Bush threw out the first ball at Game 3 of the World Series at Yankee Stadium and the city braced against continued warnings of credible threats of more terrorist attacks.
Neuroblastoma (NB) is a heterogeneous, and particularly malignant childhood neoplasm in its higher stages, with a propensity to form metastasis in selected organs, in particular liver and bone marrow, and for which there is still no efficient treatment available beyond surgery.
The NOS3 transcriptional activity was also highly correlated with disease staging, once its highest level is reached at the pT2 stage, when the angiogenic stimulus is required for tumor cell dissemination and metastasis.
Although MRJPs are the major protein components of the royal jelly, we only found one MRJP member, namely MRJP7 (NM_001014429.1) expressed at its highest level at the nurse stage among the three stages.
The miRNA, bmo-mir-2766 was ubiquitously expressed in all four developmental stages with its highest level found in pupae.
Proteasome activity has been shown to be at its highest level during the early stages of differentiation in human adipose-derived stem cells [ 56] and reduced as stem cells become differentiated.
Grimshaw's plan calls for a saddle-shape roof, rising eight stories at its highest point, over an elevated stage, and seating for 5,000.
