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But that's the machinery conserved across existing biological species changes to it, especially its functionally constrained domains, have (almost) inevitably been detrimental to an organism's survival.
It is here that design becomes a competitive advantage as users find it difficult to switch to a competitor's product because it "feels weird" even if its functionally works just as well.
The secondary structure of the Core region and the location of its functionally important residues suggested that it could be structurally related to cellular methyltransferases with a Rossman fold [ 11].
It stands to reason, then, that with its functionally weak NLS, JC virus VP1 is distributed in both the cytoplasm and the nucleus, whereas with its efficient NLS, SV40 VP1 is exclusively localized to the nucleus.
Egypt's new capital, too, is going to be built on sand – to the east of Cairo, its functionally inadequate predecessor.
Xbox One, then, is now the same price as its rival, the PlayStation 4, which Sony chose to launch without its functionally similar camera peripheral.
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Although the front-end nonlinearity model did not explain the phenomenon of fly glider perception, future work should investigate whether its merits make it functionally relevant for motion processing in other contexts or species.
Its predominant emphasis on race renders it functionally indistinguishable from the rigid quota system it employed between 1995-1998.
It was home to the Miller Cardboard Company from 1931 to 1967 when it had become, like so many of its neighbors, functionally obsolete.
Future work will have to reveal if it is cause or consequence and to what extent its downregulation functionally contributes to aging or even to tumor suppression during aging.
And reMail retains its full functionally offline, while the iPhone's search often requires a data connection to search older messages.
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