Sentence examples for its essentiality from inspiring English sources

Its essentiality is derived from the fact that it is the only enzyme that is able to introduce negative supercoils into DNA which is critical in cellular processes like replication, recombination and transcription that depend on the unwinding of DNA strands.

iRsp1095 also predicts the reversibility of the NADH dehydrogenase complex and its essentiality during photoheterotrophic growth on succinate, where it plays a key role in oxidation of ubiquinol.

Owing to its essentiality and specificity to the malignant cells, it may serve as a valid anticancer drug target, and indeed active compounds that target telomerase are already in advanced phases of clinical trials (Shay and Wright, 2005).

The case of pantothenate, the only essential vitamin with a clear metabolic effect is unique, as its essentiality is strain-dependant.

Through good times and bad, the fund's mission has not wavered, and its essentiality is underlined in the present economy, mired in a long slump.

The author of Juve! Juve!, Egilberto Martin, wrote: "For the European migrant the code of soccer, besides its essentiality as a sport, represents also a piece of that gigantic mosaic which makes up his socio-cultural structure and has retained it in spite of the mockery, the popular derision, and the powerful hold of other football codes, and in Victoria, by Aussie Rules".

Of the seven, we chose to focus on Rv3802c because of its location in a mycolic acid synthesis gene cluster, its putative essentiality, its ubiquitous presence in actinomycetes, and its conservation in the minimal genome of Mycobacterium leprae.

In addition, the importance of Rv3802c is supported by its putative essentiality, its ubiquitous presence in actinomycetes, and its unique conservation in the minimal genome of M. leprae.

The expected and predicted dispensability of ACIAD2907 was yet contradicted by its experimental essentiality.

Therefore, strong molecular and protein biomarkers are needed for the confirmation of genotype-based infection of JE virus in patients as well as its therapeutic essentiality accordingly.

But it seems logical that PPK due to its facile reversibility and its stage specific essentiality would turn out to be a prime candidate.