Notable amongst these are its use in elucidated mechanism(s) for signal transduction, various aspects of cell biology, tumourigenesis and metastasis, resistance to cancer therapeutics, and the host's response to a pathogen.
Based on the assumption that altered gene profiles during plant-microbe interactions can be correlated with symptoms, gene ontology and annotation, we believe that Xcc represents a typical example of how the bacterial pathogen can manipulate the host systems in its favour as elucidated previously in different studies [ 3, 4, 11, 35, 36].
Recent work by several groups has examined the organization of directional tuning in barrel cortex (BC) and its afferents [8] [12] and elucidated mechanisms of directional preference in cortical neurons, showing how synaptic responses vary systematically as a function of the direction of whisker deflection [13] [15].
Soon after the structure of fumonisin B1 was elucidated, 77) its similarity to sphinganine led to Ron Riley and my laboratories to explore if it might affect sphingolipid metabolism and the discovery that fumonisins are potent inhibitors of ceramide synthase.
We further detected its presence in the elucidated cpDNAs of Pinus spp. (Wakasugi et al. 1994; Noh et al. 2003; Cronn et al. 2008), Picea sitchensi (Cronn et al. 2008), Abies firma, Ce. deodora, and Larix occidentalis (Parks et al. 2009) but its absence in Keteleeria (Wu et al. 2009), Cathaya, and Ce.
Moreover, in Cathaya, its trnT-GGU (in SSC), psaM, and ycf12 (in LSC) are single rather than duplicated as in other elucidated Pinaceae cpDNAs, and its SSC region has a unique pseudogene, ψpsbB, located between trnE- UUC and trnY- GUA (supplementary fig. 1, Supplementary Material online).
Sabatini identified mTOR as a graduate student and has since elucidated numerous aspects of its namesake pathway.
The mechanism/relation between the bacteria and ZnO-MFs and its antibacterial activity have been further elucidated via Bio-Transmission electron microscopy (Bio-TEM) images.
Thus while group membership can be tentatively established, the topology of the group, or the interactions between its members are not necessarily well elucidated.
To date, we have focused on physician patient communication as the cause of medical litigation and have elucidated physician liability and its cause by analyzing medical lawsuits and quantitatively assessing physician patient communication [ 17– 23].
