In addition to its Ig1/Ig2 dependent role in inhibiting Slit-Robo1 repulsion that we have described here, Robo2 has at least three other distinct axon guidance activities that can be attributed to different structural elements of the receptor.
How many times will it require before Congress stops its co-dependent role of aiding and abetting the administration's addiction to saber rattling?
We reasoned that if PTEN regulates HR via its AKT-dependent role in the G2/M checkpoint, then inhibition of AKT would rescue HR in PTEN-depleted cells.
Similarly, the study by Moriwaki et al. demonstrated the kinase-independent role of RIPK3 in inflammation, which is again different from its kinase-dependent role in necroptosis.
In our study we have cloned and characterized this novel Myc gene and its dose-dependent role in apoptosis and cell proliferation in vivo.
Originally identified as an adhesion molecule (Takagi et al., 1995), attention shifted to its VEGF-dependent role in binding and regulating the signalling and trafficking of VEGFR2 in ECs (Ballmer-Hofer et al., 2011; Herzog et al., 2011).
Our findings demonstrate a consistent pattern of functional deficiency and provide further support for a helicase-dependent cellular function of RECQL4 in addition to its Nterminus-dependent role in initiation of replication, a function that may underlie the phenotype of RECQL4-linked disease.
Hamilton, for his part, never felt comfortable in a dependent role.
And so Achatz is willing, while his body heals, to play an odd, new, dependent role in his kitchen.
Dunwiddie, T. V. & Diao, L. Regulation of extracellular adenosine in rat hippocampal slices is temperature dependent: role of adenosine transporters.
Humanity plays an important but entirely dependent role – dependent upon the integrity of the web of life itself, with Spirit at the center.
