Sentence examples for its critical function from inspiring English sources

It is possible that ATF7IP can fulfill its critical function in the maintenance phase of XCI as part of a dynamic interaction with the Xi that cannot be captured by immunostaining approaches.

The complex of proteins involved in this information processing is known to neuroanatomists as the post-synaptic density, because the proteins stick together as a visible blob, but the name does scant justice to its critical function.

Besides its critical function during ILC1 development, T-bet is required for the maintenance of ILC1 cells and production of ILC1 effector cytokines (Klose et al., 2014) (Fig. 4).

Although TCF1 is expressed before Id2 during ILC development, its expression is maintained even after the ChILP stage, which is consistent with its critical function in the generation of ILC2 cells through both GATA-3-dependent and -independent mechanisms.

At this later stage, Arc might promote survival through its critical function in consolidating LTP [19].

p53 is one of the most frequently altered tumor suppressors in colorectal cancer and due to its critical function in cycle control [12], [13].

This criticality is mainly due to its critical functions, such as governing the transport of both the reactants and by-products, maintaining a delicate balance between the water removal and membrane hydration levels, offering continuous mechanical support to the thin catalyst layer (CL), and providing sufficient pathways for electron transport.

Given its critical functions in gene regulation, it is not surprising that DNA methylation has a crucial role in the development of various cancers including AML (Baylin and Jones, 2011; Schoofs and Muller-Tidow, 2011).

In addition, Apple said it was working with ISPs to shut down networks of servers hosted by the malware authors, which the code - known as Flashback - relies on "to perform many of its critical functions".

Earlier, Apple also said it was working with ISPs to shut down networks of servers hosted by the malware authors, which the code relies on "to perform many of its critical functions".

One of the major constituents of the synovial fluid that is thought to be responsible for chondroprotection and boundary lubrication is the glycoprotein lubricin (PRG4); however, the molecular mechanisms by which lubricin carries out its critical functions still remain largely unknown.