Sentence examples for its compartmentalization from inspiring English sources

Unfortunately, due to the high amount of NE present in CF airways, its broad range of substrates, and its compartmentalization as both a free-floating, mucus-associated, and membrane-bound enzyme [55], the design of inhibitors and modes of administration have to be significantly improved to attain therapeutic efficacy [159].

This privatization of Hinduism leads to its compartmentalization and growing irrelevance.

In transgenic Arabidopsis, site mutation of S33G disturbed phosphorylation modification of VER2 and changed its compartmentalization.

In light of the data described above, we re-analysed its cellular localization in fetal, post-natal and adult mice by ISH to set the stage for further comparative studies concerning its compartmentalization across the vertebrate Phylum.

Our data suggest that O-GlcNAc glycosylation participates in the vernalization response in wheat, and phosphorylation of VER2 is necessary to mediate O-GlcNAc signaling and its compartmentalization induced by vernalization.

To our knowledge, this report provides the first demonstration for a role of Tyr-phosphorylated AKT in its compartmentalization, which allowed us to delineate its critical role in AKT kinase activation, its potential to initiate neoplasia in mouse prostates and promote disease progression in human breast cancers.

We wondered what is the mechanism that drives its differential compartmentalization during the cell cycle.

To investigate the role of AKT Tyr176-phosphorylation on its cellular compartmentalization, we generated phospho-antibodies that specifically recognized Tyr176-phosphorylated AKT or pTyr176-AKT (details in SI methods).

Although cyclic adenosine 3'-5'-monophosphate (cAMP) has been recognized as an intracellular second messenger for decades, a detailed understanding of its regulation, compartmentalization, range of subcellular targets, and interactions with other second messenger systems has been difficult to reach, especially in complex tissues.

The neural localization of the 50 kDa species and its nuclear compartmentalization suggests that these may be key Thap1 species controlling neuronal gene transcription.

Also Tu et al. explain the cycle and its time compartmentalization in terms of metabolism and redox balance [ 4, 32, 39].