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It describes the role of Heat Shock Protein 90 and its autoregulation, while the degradation and aggregation processes are simplified in a single step.
The switching on/off depends on the magnitude of sky brightness, and it is not necessary to update an astronomical clock or timer with the passage of days, since its autoregulation is autonomous (Trueblood and Russel 1985).
At this time, the mechanism by which Npl3 functions in its autoregulation by allowing the selection of an alternative termination site remains unresolved.
While the proposed initial trigger of AtbZIP60 activation by induced-conformational change resembles the mammalian ATF6 mechanism, its autoregulation is similar to that of XBP1 in mammalian cells.
While we noted that both NaHS and PAG affected little the concentration of plasma H2S for sham groups, this led us to hypothesize that, under physiological conditions, the H2S level in plasma may keep its balance by its autoregulation.
Inspection of the UCSC RepeatMasker tracks of the regulatory regions of Oct4 indicates that its autoregulation region does not seem to be affected by repeats, cf. Figure 1, pink box.
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The correlation between IME1 copy number and the maximal level of IME1 RNA was found to be non-linear (Figure 4A); Rather, it fitted a quadratic trend (ie, a polynomial of order 2) probably resulting from its positive autoregulation [9], [11], [16].
In tammar males, SOX9 (Fig. 1b) rose in the gonad, initially in concert with SRY, but continued to increase after SRY expression fell, consistent with its suggested autoregulation [ 37].
As shown in Figure 10, both polypeptides display high identity after 70 amino acids of the M.SsoII N-terminal domain known to be involved in its gene autoregulation [ 11].
It has been shown that TS controls (suppresses) its own synthesis (autoregulation) by binding to an untranslated region of TS mRNA, and that FdUMP leads to an induction of TS by deregulation (derepression) of TS synthesis (Chu et al, 1991b).
Taken together, these results indicated that 4OHT may promote this ERα ligand-independent pathway in ERα-negative breast cancer cells, activating the MAPK-mediated phosphorylation of ERα, which may contribute to its own expression (autoregulation) [ 25].
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