Exact(4)
The first iteration identified many non-man made features such as rivers, streams and shadows in forestry plantations.
A PSI-BLAST search started with one of the Csf1 proteins (AFE_1038, Acidithiobacillus ferrooxidans) after first iteration identified a weak (not statistically significant) similarity with the Zn-finger sequence of Cas10 proteins of the Crm2 family, and its predicted secondary structure is comptabile with the treble clef fold.
The second iteration identified additional flagellins, followed by the type E botulinum toxin (BoNT/E) from C. butyricum with an E-value of 0.05 [23% sequence identity over residues 88 406 of flagellin and 727 1045 (region II) of BoNT/E, see Additional File 2 for the alignment].
The first iteration identified very similar CRC Types 1 and 2 as before (Fisher exact p-value < 2.2*10-16), and 68% and 71% (p-values < 9.9*10-16) of the genes that were previously found to be up-regulated in CRC Types 1 and 2, respectively.
Similar(56)
That link was deemed "likely" (which means probability of 66%) in 2001, and "very likely" (90%) in 2007.The latest iteration identifies radiative forcing, the difference between the amount of heat coming into the climate and the amount reflected back, as the immediate cause of warming.
The analysis, which compares the current framework and guidance with an earlier iteration, identifies a shift towards deliberation; deliberative norms are present, and even dominate recent guidance.
Equally striking is the effect of BSBn, through the recognition of a mutation doublet by SHRiMP2 in the second iteration, identifying a new descendant branch off the MFC that occurs at a much higher proportion than the other descendants, suggesting either an earlier occurrence or a relatively faster growth rate of this subclone.
In the end, the model with seven factors was the most stable (e.g. converging in a reasonable number of iterations, identifying factors which make sense in the context of the social ecology theoretical framework and maximizing the explained variance), and also captured a coherent picture of dimensions of social vulnerability in which the loading of individual variables made sense.
At each iteration, we identified significantly differentially expressed genes (FDR ≤ 5%).
After three rounds of iteration we identified 491 manually annotated CSEPs including the 248 predicted previously [ 10] (Additional file 1).
At each iteration, we identified changes encoding non-synonymous substitutions (encoding a different amino acid than the original base, or a stop codon).
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