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The majority of patients (N = 18, 90%) were ECOG-PSR 0 or 1; two patients were ECOG-PS 2. Patient and clinician input led to the development of 59 preliminary scale items (items not shown here).

The first factor with an Eigenvalue of 10.62 explained 48.3% of the variance, the second added 6.0% to the variance with an Eigenvalue of 1.33 and the third another 4.6% with an Eigenvalue of 1.03, all three contributed to a cumulative 59% of variance explained (full analysis for all items not shown here).

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The loadings indicated that an index derived from the first component was close to an average of all ten items (results not shown) and the correlation between a simple additive sum of the ten items and the first component was 0.997 p<0.0011).

Overall, less than 7percentt of the sample responded, "Don't know" to one or more items (results not shown).

Overall, less than 3% of the sample responded "I don't know" to one or two items (results not shown).

We observed minor differences when the analysis was repeated with the outcome variable based on restricted items (data not shown).

Of note, fewer patients completed the questions concerning sexual functioning and enjoyment compared to the other items (data not shown).

There were no significant differences between "middle age men" and other men in all items (data not shown).

On the GBS-ADL, there were no differences in the separate items (data not shown) or in total score.

The results of these items are not shown, because percentage agreement and kappa coefficients based on such small numbers are unreliable.

As a result, the Delphi process led to semantic changes in three of the translated items (data not shown, details are readily available upon request).

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