Sentence examples for it would not be functional from inspiring English sources

Nevertheless, given that the NTE is necessary for the activity of some full-molecule ABC transporters, we suspect that even if a truncated polypeptide were generated in this mutant allele, it would not be functional [23], [24].

Nevertheless, if a truncated 35 kDa polypeptide in this allele were stable, it would not be functional since the deletion removed an essential Cys57 residue of the catalytic triad that is located in the conserved N-terminal part of PC synthases (Figure 1B, [26] [28]).

In this sense, in a previous study, we detected p21 in the cytoplasm of epithelial cells in in situ carcinomas, and this suggests that the p21 cytoplasmic product does not reach to enter the nucleus, and therefore, it would not be functional and would not contribute to the cell cycle arrest [ 27].

An overload of ionic iron is correlated with DNA oxidative damage.[7] These metabolic pathways would not be functional in dried bloodstains.

If the F-ORF would not be functional at the protein level, one would expect the presence of within- and between-species "coding disablements", such as the numerous frameshift mutations and premature stop-codons seen in M-ORF sequences.

A clear inference is that even the simplest, ancestral NCLDV would not be functional without these genes.

Thus, the hypothetical protein product of Lerp F6 would not be functional, and as a truncated peptide, would likely be unstable.

The presence of the frame-shift in exon 4 would create a truncated ORF of 144 residues that does not include the PLP-binding lysine residue, consequently the protein would not be functional (Fig. 5C).

For example, if a replication initiation factor duplicate was not in sync with the expression of other components of the replication machinery, the duplicated factor would not be functional and eventually eliminated from the genome.

However, the next step of tooth development, during which enamel matrix proteins are deposited, either could never be activated or if it was (in the lack of data on the promoter sequence we cannot demonstrate that the AMEL gene is not translated) the protein would not be functional, and enamel will not form.

It would not be unreasonable to conclude that a functional deficiency of FABP3 in humans may lead to cognitive dysfunction.