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These results demonstrated that whereas EGFR was retained in early endosomes upon EGF stimulation in RBE cells, it was sorted to lysosomes quickly in MMNK-1 cells.
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Our findings support a model whereby Pex3 is inserted into the ER membrane where it is sorted to an ER subdomain dependent on its N-terminal signals.
"It was sort of eerie to watch," Minsky recalled.
"It was sort of appalling to me," Ms. Harada said.
And I thought it was sort of dishonest to leave those moments out.
But it was sort of beginning to happen, but he's been more articulate about it.
It was sort of surreal to watch".
It was sort of a shock to people.
It was sort of beyond our dreams to go there.
"It was sort of... they were ready to go home.
It was sort of more ….they tried to force it on me".
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