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It was originally recognized as a mediator of the DNA damage response, preventing cell cycle progression so that cells could repair DNA damage.
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PTHrP was originally recognized for its beneficial effects on skin, cartilage, placenta, and bone development (Maioli et al. 2002; Guntur et al. 2015).
NR4A1 was originally recognized for its role in cell proliferation and differentiation.
These cases have been interpreted as signs of lineage plasticity of the underlying B-cell neoplasm, a phenomenon that was originally recognized in mouse models27.
Called simply Cocker Spaniel in the UK, this is the breed that was originally recognized by The Kennel Club (KC) in 1892.
The bba64 gene was originally recognized to encode a highly immunogenic lipoprotein found amongst a variety of other genes that were differentially expressed in response to environmental parameters that mimic a feeding tick [6], [7], [9], [12], [14], [15], [25].
GSK-3β is a serinethreonine kinase that was originally recognized as a kinase that phosphorylates glycogen synthase.
GSK-3β is a serine-threonine kinase that was originally recognized as a kinase that phosphorylates glycogen synthase.
EMT was originally recognized as a critical step to metazoan embryogenesis and in defining structures during organ development [ 27].
Autophagy was originally recognized as a crucial prosurvival mechanism to supply the cell with nutrients under unfavorable grown conditions [ 4].
CD30 is a member of the TNF receptor superfamily and was originally recognized as a marker of Hodgkin and Reed-Sternberg cells in Hodgkin's lymphoma [ 4].
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