The clinical score is a crude instrument for measuring a clinical effect, as it is observer-dependent and may therefore suffer from low objectivity.
While FMD remains the gold standard measure of endothelial function, it is observer-dependent and difficult to standardise in multicentre studies.
It would be Observer's first acquisition in the United States.
"When I met him," he told The Observer, "it was like meeting the Pope".
It was The Observer which sounded the clearest dissenting note.
It was The Observer, in fact, that brought the three of us together.
It was, an observer recalled, the face of a man in extreme terror, retreating from "the ray of death".
We knew that, and they knew that too: it was the Observer that saved the leadership of the ANC".
Obviously, results of such qualitative analysis and conclusions from it may be observer-dependent.
The variation of the second analyses was almost the same between the observers as it was within the observers.
It was in The Observer — not in its sister paper, The Guardian.
