However, it should be noted that the L. japonicus PRR3 gene might have been disrupted (or it is non-functional), because our inspection revealed that its coding-sequence is separated into three currently annotated ones (LjTo8o17.180, 130, and 120).
As she says of the Swimming Reindeer: "The crucial point of this piece is that it is non-functional.
The farnesylated form of p53 resided mainly in the cytosol, where it is non-functional.
Using E. ockendeni primers [105], one locus exclusively amplified in the Lowland Clade, suggesting it is non-functional in the Upland Clade.
One explanation might be that the function of Rap1/Sfp1/Fhl1 affinity is context independent, leading even unconserved affinity to be functional, whereas for other TFs, a uniform background level of N U is found throughout the genome (because it is non-functional outside of the proper genomic context, and therefore not selected against).
The parameter has been retained for now but it is non functional.
A more realistic model is where GluRS(C) was appended to GluRS(N) before bacterial phylum-divergence but because the acquired GluRS(C) was non-functional, it was lost and regained several times, probably via intra-bacterial HGT, before becoming functionally compatible with GluRS(N) in a synchronous way [ 26, 27].
Notably, cysless GFP-tagged variant of Cdr1p was non-functional.
Kizner said the "Twitch Prime" link was non-functional when clicked, and redirected him back to the Twitch homepage.
(The dog puns are references to the 404 pages featuring the dogs of Amazon that appeared when the site was non-functional).
Functional activity of the molecule was not adversely altered by mutations in the first and second loops; however, the 61Tyr-->Gly mutation was non-functional.
