The basic technology was initially utilized in the perfume and cosmetics industry when infusing flowers or herbs/spices.
In 1982, European drug manufacturers developed mifepristone, which was initially utilized as a contraceptive, but is now generally prescribed with a prostoglandin to induce abortion in pregnancies up to the fourth month of gestation.
Rapamycin (or Sirolimus) is a macrolide antibiotic that was first isolated from Streptomyces hydroscopicus and was initially utilized as an antifungal agent [ 1, 2].
The G. max expression atlas [ 53] was initially utilized for investigating gene expression patterns of HD-Zip genes in 14 tissues of soybean.
In this way, the metabolite-centric flux-sum analysis (FSA) was initially utilized to evaluate the structural and evolutionary properties of cellular metabolism in E. coli [ 22, 23].
A new approach in the form of neoadjuvant chemotherapy was first reported in the 1970s and was initially utilized to convert unresectable tumors to smaller tumors making them more amenable to local control with either surgery or radiotherapy.
This approach was initially utilized with 1,4,7,10-tetraazacyclododecane-N′,N′′,N′′′,N′′′′-tetraacetic acid (DOTA) to yield the peptide derivatives such as DOTA-TOC or DOTA-TATE for Ga-complexation which subsequently allowed tumor-receptor-based PET imaging.
The experimental results are initially utilized to validate the flight dynamic model, and several appropriate conclusions are drawn.
Image segmentations were initially utilized to separate the aerial photos into parcel sized objects, and were further used for detailed land type identification within the parcels.
ASD data were initially utilized to help determine allocation of resources and to track clinical outcomes; later, to replace case surveillance as the primary means to monitor trends in OIs; and later still, to monitor treatment, survival, and outcomes in the HAART era [10] [18].
It was, initially, applauded.
