It was efficacious against B-RAF as well as K-Ras driven xenograft models and showed despite being orally bioavailable and not a P-glycoprotein substrate much lower brain/plasma exposure ratios than PD325901.
While it did not protect against sexually transmitted infections (STIs), it was efficacious, user-controlled, and could be used without a partner's knowledge.
33 The trial showed that early administration of high-dose rosuvastatin (40 mg) could improve coronary microvascular function and short-term outcome in patients treated with PCI for acute myocardial infarction, and it was efficacious and safe.
This argument ignores the possibility that, even when a treatment is efficacious, there may be type 2 errors (i.e. failure to find efficacy of a treatment even when it is efficacious).
"I think what they should say is there is not enough evidence to state whether it is efficacious".
If a single property is both mental and physical, Completeness and No Overdetermination force us to say that it's efficacious only qua physical, not qua mental.
The issue was whether the supernatural grace in question is efficacious by itself, in other words, intrinsically efficacious, or whether it is efficacious only by virtue of the independent, divinely foreknown cooperation of the one who receives the grace (Vansteenberghe 1928, #2154 65).
Under this situation, the link's travel time related relationship can be inferred, and it is efficacious for planners or engineers to make a decision for a long time.
Monsanto, which makes Roundup, claims that since its discovery in the early 1970's, glyphosate has become the world's most widely used herbicide "because it is efficacious, economical and environmentally benign".
It is efficacious in inhibiting the proliferation of a broad range of cancer cells as well as solid tumors.
Given that clofazimine is already used in the clinic, albeit for a completely different indication, we wondered whether it is efficacious in animal models of organ transplantation.
