Sentence examples for it was difficult to formulate from inspiring English sources

These initial biological results suggested that subtle structural changes to the phenyl and acetamide bond of C-pseudonucleosides could have a significant effect on T cell proliferation bias, although it was difficult to formulate a rigorous structure-activity relationship based on the observed activities.

Another limitation of the tool is that it was difficult to formulate clear-cut criteria to demarcate high and low quality.

Participants in focus group 2 stated that it was difficult to formulate goals due to the uncertainty of the care process and the disappointments of the patients when goals were not reached.

It did not take Arthur long to discover that it is difficult to formulate a useful model in conventional mathematical terms.

Intelligibility varies so much with the speaker and the hearer, however, that it is difficult to formulate firm criteria on that basis.

It is difficult to formulate a distinct definition for each of these terms, because their use largely overlaps in the literature despite individual preferences.

But it is difficult to formulate the reductionist claim precisely.

It is difficult to formulate this point precisely, however.

Therefore, it is difficult to formulate adequate conclusions [2].

Owning to the different train and coupler types, it is difficult to formulate uniform regulations for train to train rescue.

However, for structures without plans or insufficient structural details available it is difficult to formulate an analytical solution, especially for concrete structures where internal reinforcement details are needed to determine section capacity.