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Similarly, performing additional rounds of selection (be it very stringent, normal, or lenient) also does not substantially change the observed noise levels of the selected promoters.
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Also, 2) it is very stringent in that it will only recruit and co-assemble NGS reads whose bases overlapping the target sequence are in perfect agreement.
It is very stringent and yields robust transcriptomic signatures.
As an example ArrayExpress Atlas (http://www.ebi.ac.uk/microarray-as/atlas/) gives the opportunity to identify strong differential expression candidate genes in conditions of interest (i.e. irradiation conditions) but it adopts very stringent statistical filters.
"It's a very stringent board," he said.
Feinstein counters that it "puts some very stringent parameters on" the program.
"It is a very stringent regulatory environment that doesn't allow companies to manage their business on a day-to-day basis".
"It's a very stringent standard to get SSI," said MaryBeth Musumeci, associate director of the foundation's Program on Medicaid and the Uninsured.
We originally used H3.2 as an antibody control because we detect lower levels of H3K64ac on this subtype and therefore we considered it as a very stringent antibody control.
In addition, the iterative convergence criteria have a major impact on the predicted age of air, where it is shown that very stringent criteria in terms of scaled residuals are required to obtain accurate results.
Since this selection procedure is not very stringent, it requires exact timing of incubation steps and results sometimes in high background making purification of positive clones difficult.
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