They benefit greatly when you have a mass migration of people that makes it very difficult to ascertain who is legitimate, who is illegitimate, who is dangerous, and who may be safe.
Annexin-V exposure, even though considered as an early event of apoptosis, had been initially characterized in necrotic cells.9 Likewise, it is well established that most apoptotic cells later shift to necrotic status owing to membrane permeability.10,11 This makes it very difficult to ascertain the nature of cell death signaling from snapshot events of analysis using this assay.
"There is no objective test for backache so it's very difficult to ascertain its seriousness," explains Dr Levinson.
"It was very difficult to ascertain the facts and names as it is a very conservative area, deeply entrenched in tribal customs and traditions," said Farid Ahmed, the provincial coordinator of the Human Rights Commission of Pakistan, in a telephone interview from Quetta.
In any event, just from video images and photographs it is very difficult to ascertain exactly what the cause of such an incident would have been.
It is very difficult to ascertain when tattooing came about in human culture because there are few written records and scientists must instead look at the archaeological record.
However, because of the complex nature of eating behaviour and the chemical heterogeneity of foods, it remains very difficult to ascertain which aspects of diet, in what quantities and over what time-frames are responsible for modifying risk.
In general it is very difficult to ascertain whether biomarker proteins are generated by the cancer itself or by secondary effects, such as immune response.
Given the absence of the IR from the Chlorella genome, it is very difficult to ascertain whether the transcription direction of the rRNA operon changed and whether genes were relocated from one genomic region to another during the evolution of trebouxiophytes.
While it is very difficult to ascertain precisely which model applies to a particular cellular context, in a broad simplification one could say that in one conformation, the 'opposite conformation', the tetramer can bring together different cell membranes, while in the other conformation, the 'lateral conformation', the tetramer can act as a platform for association with other proteins.
It still remains unknown, and it will be very difficult to ascertain, whether many of the most prolific grunters intentionally grunt to interfere with their opponent's performance.
