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In practice, if an allocation ratio for a treatment is below a threshold value (e.g., 5%) it would likely be set to 0. Although we do not consider FOCUS4 comparable to the designs in this paper, due to it utilising a hierarchy of biomarkers, the question remains of whether a group-sequential design which specifies futility-stopping boundaries would be a superior choice to our BAR design.
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It utilised viral marketing like no film before and despite its inauspicious beginnings, managed to make $248m worldwide.
It utilised marginal farm-land, which may have contributed to its design; the heathland and light woodland south of the castle would have been ideal for grazing deer.
In 1999, it utilised the UK City of Architecture and Design award to similar effect.
At first, it utilised postcards, phone-a-thons, sit-ins, church groups, rallies and campus organisations, but its reach grew enormously when it embraced technology.
Designed to absolutely not be mistaken for advertising, its proportions were based upon Roman precedents, with perfectly circular "o s, while it utilised a quirky diagonal dot for periods, "i"s and "j"s.
Rocha's collection was most powerful when it utilised sumptuous upholstery fabrics.
Secondly, it utilised various characteristics of actors, and relations such as hierarchical and equivalence are built among actors.
It utilised an ex vivo isolated perfused rat lung (IPRL) model that retains the intact lung architecture while eliminating the confounding issue of systemic pharmacokinetics.
The iPhone wasn't the first touchscreen smartphone either, though it utilised capacitive technology and a UI that ensured it was finger-friendly and crucially bundled a data connection at the point of sale.
It utilised image processing algorithms from the Functional Magnetic Resonance Imaging of the Brain (FMRIB) Software Library FSLL) [21], C3D [22], and NIFTIREG [23] software packages for image registration and re-sampling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com