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Whereas imatinib had no effect on elastase-induced emphysema in WT mice, it significantly exacerbated the post-elastase lesions in the Sesn2 KO lungs, suggesting that PDGFRβ signalling directly contributes to lung protection in these mice (Fig. 5B).
While verapamil had no effect on aortic architecture in WT mice, it significantly exacerbated the histological changes seen in the ascending aortic wall of Marfan mice, both qualitatively and quantitatively (interaction effect: p < 0.0001, Figure 2C).
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"I'm of the view that you just can't meet the standard now that Obama set out: Does it or does it not significantly exacerbate the problem of carbon pollution?
It would significantly exacerbate carbon pollution and climate change -- while only creating 35 permanent jobs.
Last June, the president vowed he would not approve the pipeline if it would "significantly exacerbate the problem of carbon pollution".
In June, President Obama said that the building of the full pipeline – on which he alone has the ultimate thumbs up or thumbs down – would be approved only if "it doesn't significantly exacerbate the problem of carbon pollution".
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In previous remarks, Mr. Obama has said he will approve the pipeline only if it does not "significantly exacerbate" the problem of carbon pollution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com