Within the non-hematopoietic cells (e.g. prostate, colon, breast, neuronal/astrocytes) that express Lyn, its role in activating/inhibiting various signals still requires further elucidation, however, most studies so far point to it being a positive regulator [ 36, 37, 54- 56].
However, the specific biochemical interaction between thrombin and osteopontin and its role in mediating breast cancer cell malignancy requires further elucidation.
Whether ppk1 is used to store Pi as polyphosphate for surviving periods of extreme Pi-limitation, or whether it is used to drive transport equilibria by acting as a phosphate sink to maximize uptake requires further elucidation through laboratory work.
This study uncovers a crosstalk between distinct subcellular compartments as yet another stress response mechanism whose regulation requires further elucidation.
The mechanism by which the human KL-VS variant affects cognition also requires further elucidation.
At the same time, the cytotoxic potential of C60 in photodynamic therapy on drug-resistant cancer cells requires further elucidation.
Evidence for a beneficial effect of fluid intake on intermittent, resistance and sport-specific exercise performance and cognitive function or mood is less apparent and requires further elucidation.
Evidence indicating a benefit of fluid intake on intermittent (10 trials), resistance (9 trials), sport-specific (6 trials) and balance (2 trials) exercise and on cognitive performance (15 trials) was less apparent and requires further elucidation.
However, the mechanism underlying this increase requires further elucidation.
The detailed identification of this material requires further elucidation, and is currently under investigation.
The balance of these chemokines may be critical in the tumour microenvironment and requires further elucidation.
