The digital transformation of sequential data employed is well suited to this sort of global analysis, whereas character-based search tools and diagnostics do not naturally lend themselves to this task, as it is problematical to generate a "mean" sequence representing a group of sequences using characters.
In addition, it is problematical to take an arithmetic mean of a series that can include values that are negative or infinite.
To make things worse, said Dr. Ligeti of Fermilab, theorists find it problematical, for technical reasons, to compare the kaon results in a very precise or direct way to the asymmetry that the theorists put at the heart of the Standard Model.
Turkeys are problematical to raise — susceptible to disease, cold and a host of variables that seem to crop up during their four-month lives.
Quantifying CO2 impacts through the Net Present Value (NPV) is challenging, since impacts are difficult to estimate and their apportionment on an annual basis is problematical to apply.
Commenting on the Soviet and American searches: "Since the U.S.S.R., for natural reasons, knew better where the Boeing had been downed...it was very problematical to retrieve anything, especially as the U.S.S.R. was not particularly interested".
Beyond this case the presence of interallelic trans-splicing in vertebrates is problematical to demonstrate.
Managers and analysts can use it to explore problematical issues relating to access to public services in a wide range of situations and sectors.
Although the phenomenon is well established in cellular systems, it is still problematical as to whether or not it will have any utility in establishing risks of ionizing radiation to humans.
But it seems on the face of it to be quite a problematical way to support a colony.
