Understanding the nature of low vitamin D levels in adults with T1DM is important because it may potentially clarify the mechanisms of autoimmune ß-cell destruction, leading to interventions for the prevention or delay of insulin dependence by using vitamin D or its analogues.
The results suggest that low-cost changes to questionnaire design will potentially clarify the concept of work for respondents.
Polygenic effects (Pan et al, 2015) from large genome-wide association studies (Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014) could be calculated for those who do or do not use cannabis to potentially clarify some of the shared genetic risks that may underlie the association.
Additionally, our method facilitated the detection of FA, RD, and AD differences with respect to the structural geometry of each fiber bundle, which can potentially clarify regionally specific white matter abnormalities within the fornix and cingulum in schizophrenia.
Other problems that may be potentially clarified in future by using species-specific loci may include Hardy-Weinberg disequilibrium and null alleles.
It appears necessary that these interactions are mapped in detail in vitro or in a 2 hybrid system, as this could lead to predictions for the functions of dominant negative mutants and potentially clarify how different complexes are assembled.
Applying a protocol that is preferentially sensitive to detecting mnemonic mechanisms operating outside of conscious perception can potentially clarify other controversies, such as the extent to which non-conscious memory mediates hippocampal-dependent tasks [9].
Factoring in the follow-up status of individuals would potentially clarify the characteristics associated with long-term community placement, thus providing another avenue to hone the Q + Index and maximize the return on investment necessary to assist transitionees.
Furthermore, functional studies on voltage-gated muscular ion channels with the patch-clamp technique are feasible and can potentially clarify pathomechanisms of so far unknown disease entities of the muscle cell membrane.
Routine p16 staining is not indicated for diagnostic samples due to the uncertain significance of p16-positive LSIL, 45 but it is a useful research tool for further exploring the natural history of p16-positive LSIL in conjunction with HPV genotype and/or biomarker analysis and potentially clarifying the significance of these lesions.
