Sentence examples similar to it posed a substantial difficulty from inspiring English sources

The additional germ line cells occupy locations near somatic cells of interest throughout the trunk of the worm, which poses a substantial difficulty for annotation approaches that rely on location-based features alone.

However, when ventilation is applied inappropriately, it poses a substantial risk to patient safety.

This bacterium remains endemic in parts of Asia, Africa, and the Americas, where it poses a substantial zoonotic threat to human populations.

In a letter, Mr. Campbell asked the broadcasters if the $200 million project posed a substantial public benefit.

Ms. Brown said she continued to believe that the seats posed a substantial risk to children.

The guidelines require investigators to provide notice unless it would "pose a substantial threat to the integrity of the investigation".

It posed an excellent question.

No studies have been conducted on how Cipro affects pregnancy, but the centers said it was unlikely to pose a substantial risk.

It is also shown that the associated neptunium poses a substantial proliferation risk.

Thus, difficulty in communication during patient education still poses a substantial barrier to insulin initiation in Malaysia.

The NAACP said that it typically issues travel advisories when conditions on the ground pose a substantial risk of harm to black Americans.