Thus, in contrast to IGF1, the effect of IGFBP5 on LX2 cells survival is not mediated by the IGF1R, suggesting that the effect it exerts on partly activated stellate cells is not by modulation of IGF1 signalling.
This corresponds to the situation when an incomplete word (such as "wai... ..........) is perceived and several lexical alternatives from its "cohort" are partly activated ("wait", "wail", "waif" etc., see Marslen-Wilson 1987).
Because TGF- β1 is at least partly activated by proteolytic cleavage, we evaluated the total and active TGF- β1 levels for correlations with likely candidate proteinases involved in TGF- β1 activation and with PAI-1, a presumed secondary marker of TGF- β1 activity, in the gastric cancer homogenates (Table 3).
The hypothesis is in line with the possibility that effector T cells are partly activated in autoimmune diseases [ 5, 6], thus eliciting Treg activation.
Under usual circumstances, the pharyngeal components of deglutition are bypassed, but these can be partly activated on occasion causing the small pharyngeal and mylohyoid complexes that occur with some TLESRs.
Our results indicate that PMN from SLE patients have altered function, are partly activated and are released abnormally from bone marrow.
Expression profile is suggestive of partly activated apoptosis (SMAC) and disturbances of intracellular signaling transduction cascades (down regulation of several cytokines, early genes, and regulatory proteins).
Recent studies have shown that TLRs are also expressed on the surface of a variety of tumor cells and partly activated by corresponding ligands.
No differences in the expression of CD11b or CD62L were observed (Table 3), indicating that the cells were only partly activated.
The phenotype of a cell is determined by its transcriptional repertoire, a result of combinations of transcriptional programs partly set during lineage determination and partly activated in response to intrinsic and extrinsic stimuli.
To better appreciate the complexity, we present four hypothetical patients in whom different cytokines or different cell populations may appear to predominate, even though in all patients many cells or soluble molecules are at least partly activated.
