Although some metastatic disease may benefit from surgical resection, chemotherapy is the prime therapeutic tool in advanced disease, as it aims to palliate symptoms and increase time to disease progression (TTP) as well as overall survival.
More patients in the non-Paget's control group had received chemotherapy (data not shown), reflecting the fact that their prostate cancer had tended to progress and they required more aggressive therapy to control it and/or to palliate their symptoms.
But the art that palliates Humbert's misery has not notably relieved the distress of reviewers, most of whom have felt obliged to ask themselves, "Why has the author done this horrid thing?" Some have concluded, rather desperately, that he hasn't done it at all.
The new annex palliates some of the tower's most glaring design problems.
In the end, however, he palliates the differences, leaving the possibility for some way to harmonize the two (1178a30).
It induces PSA declines of ≥50% in 29 62% of patients, achieves OS benefits in both docetaxel-refractory and chemotherapy-naïve patients, delays and reduces skeletal-related events, and palliates pain [ 4, 9] (Table 1).
Mitoxantrone plus prednisone (MP) palliates bone pain in 30% of patients but does not increase survival (Tannock et al, 1996).
Not only is local recurrence painful and difficult to palliate, but it has also been shown that the results of surgical resection for local recurrence are disappointing[ 3, 4].
While open-heart surgery can correct or palliate CHD, it also represents the challenge of psychologically adjusting to the surgical event and associated side effects for the child and the parents.
The first two, "Understanding a good death: Physicians' perspectives" and "Whose job is it to Palliate: A changing system of care", concentrate on how physicians understand a good death and how they can practice end-of-life care from within critical and acute settings.
I know it sounds shallow, the opiate thing, needing to believe, palliating pain, but it didn't feel shallow...
