Post-remission therapy needs to be optimised, but it is likely that the needs of previously untreated patients may be different from those with relapsed and refractory disease.
The model observer can, in principle, be useful to assist human performance in CT low-contrast detection tasks and in dose optimisation, but needs to be optimised in order to extract useful information to support and predict human observer evaluations on CT images.
The tests demonstrated that each imaging modality needs to be optimised for this particular application: it is, in general, not sufficient to repurpose an existing device without modification.
In order to gain the full benefit of intensive agriculture, the pollination service needs to be optimised.
These methods have been implemented on an ensemble subsampling methodology, hence as described previously the length of the subsample, q, needs to be optimised.
Obviously, noise attenuation is strictly related to the internal gas-dynamic field that, on the other hand, needs to be optimised also in terms of pressure losses.
The development of appropriate manufacturing techniques is an essential stage in the engineering exploitation of these materials, e.g., Induction Skull Melting is one of the techniques which needs to be optimised for the casting of titanium aluminides.
The transportation of pigs needs to be optimised.
In addition, delivery method of the agents needs to be optimised depending upon the underlying therapeutic mechanisms [ 68, 69].
If a large burn excision requiring major transfusion is planned, the patient needs to be optimised for theatre and a low starting haemoglobin concentration seems unwise.
