This may occur in a Dpp-independent fashion, but it is also possible that BMP signals might be active during larval segmentation, since the expression of the BMP receptor thickveins has a segmental pattern of expression [34].
(Since it is not known how many different PMCAs might be active in snail neurones, my results strictly apply only to the total PMCA activity).
As these ligands activate different erbB receptors, it is possible that multiple erbB receptor combinations might be active in a tumor, a characteristic that could influence its response to an erbB-targeted therapeutic (Karunagaran et al, 1996).
Of this 5.6%, it would be instructive to determine the percentage that might be active.
Moreover, lrinotecan+5-FU+LV is currently the most active first-line and it is not yet known whether other second-line drugs might be active in this setting.
Based on these observations, it appears that cytochalasin B and potentially other cytochalasin congeners might be active against multidrug resistant neoplastic cells and might also be able to overcome resistance to other cytotoxic agents currently used in the clinical setting.
The team also says it has identified at least four other lunar areas that also might be active.
Bristol recently presented data on its lead Src inhibitor showing that the drug might be active in leukemia patients who have become resistant to Novartis ' \ leukemia drug, Gleevec.
Yet many Muslim men do not allow their wives even to work outside the home and are appalled at the thought that they might be active politically.
That situation is complicated of course by Gregory now being in some danger; Stan Beeman is starting to have some thoughts about whether a KGB cell might be active in Gregory's neighbourhood.
