Sentence examples for it may exerts from inspiring English sources
To further confirm the CYLD function as regulator of keratinocyte differentiation and the relevance of the JNK pathway activation as a mechanism through which it may exerts its function, we generated HaCaT cells expressing a catalytically deficient CYLD mutant (CYLDC/S) that carries the 601C/S point mutation in the cysteine box of the deubiquitinase.
If ADAM9 overexpression is involved in PDAC progression, it may exert its action either via its disintegrin domain or its metalloproteinase domain or, most likely, via both.
Exploring new insights into the molecular mechanisms of exercise reveals just how it may exert its effects.
It may exert its beneficial effect by targeting activated parietal epithelial cells as well as monocytes/macrophages.
This variant maps to an intergenic region but it was hypothesized that it may exert its functional effect via the TNFAIP3 gene.
Although MYCN activates transcription of pro-proliferative cellular networks, it is increasingly clear that it may exert its pro-proliferative action also through repression of specific target genes.
It may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation [ 29].
Either it may exert its own toxicity [ 129], or it may be metabolized into the other main conjugate p-cresylglucuronide, which also has biological effects on its own [ 69].
Since MitoQ was administered orally it is possible it may exert its effects in several different cell types and for this reason the mechanism(s) of action will require further investigation.
Thus, if NE has global effects on the chick pineal, it may exert its largest effects at the protein level, with comparatively small effects on gene expression, as is the case for NE's acute inhibition of melatonin biosynthesis [ 8].
A mechanistic network generated for beta-estradiol in this analysis (see Fig. 5) shows that it may exert its effects on the observed gene expression by interacting with ESR1 (as expected) and also through co-activators and other regulatory molecules.
