Moreover, it has recently described its role in regulating Wnt signaling and thus, it may be involved in adult neurogenesis.
Due to its accumulation profile and the characteristics of these proteins, it may be involved in regulating stress-activated signalling pathways.
The regulation of NCAM1 splicing and its interaction with known splicing regulators and with polymerase II suggests it may be involved in spliceosome assembly.
The sequence is located on the exposed molecule loop, therefore it may be involved in the interactions with other proteins.
GSK-3 expression is particularly high in brain where it may be involved in neurological and psychiatric disorders such as Alzheimer׳s disease, bipolar disorder and major depression.
Given that LRRC25 is highly expressed in myeloid cells, it may be involved in immune responses such as infection and inflammation, in addition to myeloid cell development.
Mutated forms of it may be involved in a series of reactions that ultimately enhance the overexpression of IL-1b and consequent inflammation [1].
Planarian DIS3L2 was similar to Drosophila DIS3L2 in protein sequences and, like DIS3L2 in other organisms, it may be involved in proliferation regulation (Fig. S4D).
The multi-tissue expression of prdm1a suggests that it may be involved in variety of developmental processes.
Given the unique nature of this domain, it may be involved in sensing signals which are exclusive to this kinase.
They theorized that it may be involved in progression of disease.
