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This hypothesis also suggests why it may be difficult to isolate mRNA complexes with an EJC on AUG1.
Against the background of large gene families it may be difficult to isolate BACs for a specific target gene.
Particularly in studies without control comparators, it may be difficult to isolate patients' rheumatologic diseases as the sole cause for VTEs.
Because mercury and n-3 fatty acids often travel together, it may be difficult to isolate the opposing influences of the two on child cognition.
Cripto nulls also fail to undergo gastrulation (Ding et al., 1998), so it may be difficult to isolate the contribution of these two genes in gastrulation.
Many workforce type interventions build upon existing services and it may be difficult to isolate the particular features of the intervention which are new and distinct from 'care as usual', as required for experimental or quasi-experimental design.
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Such agents may be difficult to isolate, identify, and treat effectively.
Moreover, the immunosuppressive treatment may have an impact on disease course that may be difficult to isolate.
As culling of infected animals is recommended for the eradication of the infection, it may be difficult to obtain several isolates from a herd during an outbreak.
However, although evaluation studies may provide valuable information, without explicitly examining design issues, it will be difficult to isolate the influence of specific design choices on P4P performance.
It also could be difficult to isolate from the solvent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com