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It may be difficult to characterize small arterially enhancing nodules in cirrhosis, differentiating between HCC, dysplastic nodules and transient hepatic attenuation differences (THADs).
Third, for transcript isoforms expressed in a small subset of cells in the tissue or organism of interest, it may be difficult to characterize the transcripts specific to those cells (Graveley et al. 2011; Malone and Oliver 2011).
There are practical challenges for oncologic drug development – it may be difficult to characterize the dose response relationship as often only one or two doses are studied in the target patient population, and placebo data are rarely available.
The authors identified 84.6%2222 of 26) of cholangiocarcinomas by the presence of an enhancing mass on delayed gadolinium-enhanced MRI, obtained 5 min after gadolinium injection, but found that in the absence of an enhancing mass, it may be difficult to characterize the etiology of a stricture [ 60].
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However, it may be difficult to implement continuous relative risk functions using existing dynamic modeling tools if baseline exposure information is difficult to characterize as continuous distributions or if continuous dose-response information is available only for certain health outcomes.
Unless we are able to characterize nanomaterials in soil, it may be difficult to explain their differing effects and to interpret the results of spiking studies.
Unless we are able to characterize nanomaterials in soil, it may be difficult to consider their effects and interpret the results of spiking studies using repeated drying/wetting cycles.
But it may be difficult to sell.
These dietary and lifestyle factors are all potential confounders that may be difficult to accurately characterize in epidemiological studies such as ours.
It's difficult to characterize music in simple, sweeping terms.
Mr. Stewart said that residents were generally aware of the verdict but that it was difficult to characterize their feelings.
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