Sentence examples for it markedly increased from inspiring English sources

While this demand was refused, it markedly increased the tensions between the powers.

While TGFβ1 only moderately elevated PDGFRβ expression in vitro, it markedly increased pSmad2/3 levels in cultured human VSMC and in murine fibroblasts.

UDP-glucose treatment instead resulted in a significant increase of the number of GPR17+ precursor cells, suggesting that activation of the receptor may itself promote receptor expression, and, more important, it markedly increased the number of mature MBP+ oligodendroglial cells (Figure 4L).

The maximum photosynthetic capacity (i.e. the maximum relative light-saturated electron transfer rate, rETR) calculated from the P vs. E relationship was not significantly altered by HL treatment during the initial and intermediate phase; however, it markedly increased during the late acclimation phase (>12 h) compared to the control (LL treatment, Figure 7A).

Next, we performed immunoblots for osteopontin, which is a biomarker of tumour progression [ 23], and found that it markedly increased in the advanced passage cells.

When R9 was added to either rGel alone or the CPE-G4S-rGel fusion protein it markedly increased uptake and cytotoxicity.

However, it markedly increases mortality.

Examination of intra- CFTR rearrangements adds to the complexity of diagnostic testing in CF. All this may be difficult for the couple to comprehend and it markedly increases the burden of their ART treatment and makes genetic counselling more challenging.

According to the values given in Table 2 and Figure 4, k mf in the liver was left virtually unaltered by MTF (0.004 ± 0.003 min−1, p = ns vs CTR), while it was markedly increased by STS (0.095 ± 0.051 min−1, p < 0.05 vs the CTR and MTF group), as expected as a consequence of the fasting condition.

It also markedly increased the already high level of distrust between countries.

The effort is also largely seen as a failure: Decades later, research shows the "war" has not been successful in reducing drug use in America ― although it has markedly increased incarceration rates.