It's a mechanical lock with physical keys that will maintain functionality for years.
Affinity-based open-tube capillary columns are demonstrated here to purify, enrich, and maintain functionality for a monomeric and dimeric enzyme, a low-abundance HeLa nuclear complex, and a light-harvesting octadecameric membrane protein complex.
When activated in cancer, this module can substantially affect tissue behavior, yet this occurs not in a deregulated, but in a rather coordinated manner, and thus maintaining functionality for the cell, albeit not one that is in the long-term tolerable for the organism.
Collectively, these observations underscore the significance of mixotrophy (the combination of phototrophy and heterotrophy) for the survival and proliferation of dinoflagellates living in changing environmental conditions, but do little to shed light on how the stolen organelles maintain functionality for extended periods of time.
Both kill switches were shown to maintain functionality in vitro for at least 140 generations.
The content of palmitic acid is important for maintaining functionality in the presence of increased polyunsaturated FA.
The widespread taxonomic distribution of Suf and its presence in both aerobes and anaerobes suggest this system evolved prior to the widespread oxygenation of the biosphere and thus likely evolved mechanisms or strategies for maintaining functionality in an oxidizing environment.
Robustness can be defined as the tendency for a system to maintain functionality under perturbation.
Given the recent demonstration that the flexible C-terminal region of Pdx1 is essential for catalysis [21], we sought to identify the key residue(s) in this region necessary for maintaining functionality.
However, it is not always clear how they maintain functionality.
Maintaining functionality and autonomy in elderly people is an important challenge for geriatric clinicians.
