Protein loses flexibility when a flexible residue (Leucine) is replaced with a rigid one like Proline.
The condition can often be treated effectively when it first occurs with roomy shoes, stretching exercises and bandages or straps to hold the toe in a normal position, but if it is allowed to persist, the toe loses flexibility and is trapped in its misshapen position.
"A country which is cutting its educational institutions into cripples loses flexibility and the power to innovate and is thus squandering its future," thundered Wolf Lepenies, a noted German sociology professor.
What generally happens as the body loses flexibility is that golfers still try to keep "width" in their backswing and simply lift their arms.
Our imagination loses flexibility, as we become what our world wants us to become.
It is likely that the molecular nature of the interactions underlying such a trapped substate involves complex dynamics of solvation-desolvation forces that lead to stronger hydrophobic contacts at elevated temperatures, so that the protein loses flexibility by increasing temperature.
It's easy to lose flexibility as you grow older so if you are young make sure you carry on doing these exercises so don't forget them.
"The government says that outsourcing is everything, but while it might get you an initial cheaper price, that price simply doesn't last, you lose flexibility, and it causes a great deal of unrest".
You might pull something and have to wait a while before stretching again, and you will lose flexibility once it's healed.
When Italy joined the euro it lost the flexibility to adjust its exchange rate to keep competitive pace with low-inflation Germany.
It's still difficult to drink anything, and I can hardly manage to put on socks (I'm losing flexibility every day), but altogether, I feel surprisingly good.
