Sentence examples for it lacks efficacy from inspiring English sources

This observation has provided further opportunity to investigate the reasons why in the in vivo assay model INH was highly efficacious while when tested in the in vitro assays it lacks efficacy against MIP even at higher concentrations.

The recently published Phase II clinical trial data for ABT-263 indicate that it lacks efficacy in patients with relapsed small cell lung carcinoma (SCLC), as only 1 out of 39 patients experienced a partial response, and 36 patients withdrew due to disease progression or adverse events.

Moreover bevacizumab was also investigated in combination with different drugs, such as irinotecan, CCNU, and TMZ, in children with recurrent or progressive WHO grades 3-4 gliomand althoughough the combination was well tolerated, it lacked efficacy, with no sustained responses observed [ 66].

It has been suggested that IL-10, an immune suppressor, lacks efficacy [ 72].

Eflornithine is expensive, is laborious to administer, and lacks efficacy against T. b. rhodesiense.

Recent randomized controlled trials also suggest that memantine lacks efficacy in the treatment of FTD [ 34].

They contend that the prospective controlled trials have been "inconclusive," and that failure to demonstrate efficacy should not be taken as evidence that the vaccine lacks efficacy [ 2].

However, although the humanized anti-IL-4 monoclonal antibody pascolizumab is well tolerated, it lacks clinical efficacy in asthmatic patients [ 16].

Unfortunately, available therapies lack efficacy in preventing progression to its end stage phase.

As monotherapy, however, anti-angiogenic treatment lacked efficacy in randomized clinical studies so far.

GRK2 lacked efficacy at both endothelin and alpha(1 -adrenergic receptors despite massive overexpression.